If It Causes Fewer Dangerous Major Bleeding Events. cause fewer dangerous major bleeding events than.Avoid in patients with moderate-to-severe hepatic impairment (Child-Pugh classes B and C) or in patients with any hepatic disease associated with coagulopathy.Skip navigation Sign in. Search. Loading. Close. Yeah, keep it Undo Close. Pradaxa and Xarelto:.
Use with caution in pregnant women and only if the potential benefit justifies the potential risk to the mother and fetus.Safety and efficacy not established Next: Interactions Interaction Checker Enter a drug name and rivaroxaban No Results.Pradaxa is used to prevent blood clots from forming because of a.Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
If a dose is not taken at the scheduled time, take as soon as possible on the same day and continue on the following day with the once-daily regimen as recommended.
Switching from xarelto to warfarin. comparison between pradaxa and warfarin.Create Your List of Plans Adding plans allows you to: View the formulary and any restrictions for each plan.
Caution with concomitant use of P-gp and weak or moderate CYP3A4 inhibitors (eg, erythromycin, azithromycin, diltiazem, verapamil, quinidine, ranolazine, dronedarone, amiodarone, felodipine, citalopram, escitalopram, fluoxetine, fluvoxamine, desvenlafaxine, venlafaxine).Premature discontinuation of anticoagulants, including rivaroxaban, places patients at increased risk for thrombotic events.
Unchanged rivaroxaban is the predominant moiety in plasma with no major or active circulating metabolites (50% higher in patients of Japanese descent).AUC: 29-56% decrease when released in proximal small intestine compared with gastric absorption.For people taking PRADAXA for atrial fibrillation: Do not stop taking PRADAXA without talking to the doctor who.