The purple toe syndrome is not well understood, but is thought to be due to cholesterol deposits breaking loose from the walls of blood vessels, flowing to the toe, and blocking usual blood flow to the affected toe.Warfarin has been proven to cause birth defects and increases the risk of hemorrhage in both the mother and the newborn.
If the dye is the culprit, the clinician may change to another strength tablet (which is a different color and therefore contains a different dye).For this reason warfarin is often referred to as a vitamin K antagonist (VKA).You get vitamin K from many of the foods you eat (especially green vegetables and certain oils).Normally, your liver makes these proteins and it requires vitamin K to do so.Tell your doctor if you have any side effect that bothers you or that does.Patients with a condition called protein C deficiency may be especially prone to this rare side effect.
Bleeding is also more likely to occur for people who take high doses of warfarin, or take this medication for a long. that you take warfarin. Coumadin.Whether adequate anticoagulation eliminates the estrogen-related increased risk of clotting is controversial.It may also help if you take it at the same time that you do something else that is routine to you - such as take it when you eat your dinner or when you brush your teeth at night.Other rare side effects (that occur in less than 1% of patients) include skin necrosis, purple toe syndrome, and allergic reaction.
This section is designed to answer general questions you may have about warfarin.Fish oil is a natural blood thinner than can thin the blood and.
Reducing the amount of vitamin K in your diet may both cause your INR to increase to a dangerous level and make the INR more difficult to control.For more information on the PT test and the INR, see Understanding the PT-INR Test ).
Therefore, you should keep you clinician informed of any of these types of changes and discuss in advance any changes you are planning in any of the above factors (such as going on a trip, starting an exercise program, trying to stop smoking, going on a new diet, taking an herbal preparation, etc.).If the instructions are not perfectly clear, ask your clinician to explain the instructions again or to write down the instructions for you.
However, there are a number of ways that the effect of warfarin can be reversed and thereby prevent excessive blood loss.What to do if that occurs depends on several factors (as discussed below).
Also, when you call, be prepared to report (as best you can recall) the size of any extra doses taken and the date(s) when the extra dose(s) were taken.Medication Guides will be required if the FDA determines that one or more of the following circumstances exist.Therefore, it is very important that you keep your anticoagulation clinician up-to-date on any such product(s) you are taking.