Eliquis and Xarelto are all options for patients being anticoagulated for stroke prevention from.But Jacobson and another dozen physicians interviewed by Reuters expressed similar concerns about both Pradaxa and Xarelto.Some are proposing a more rigorous monitoring regimen for when they are used.
Patients should not stop taking any prescription drug without seeking the advice of their medical doctor.Pradaxa And Xarelto: Top Heart Doctors Concerned Over New Blood Thinners.Discover how the new blood-thinning drugs Eliquis, Xarelto, and Pradaxa compare to warfarin.It was the first new oral treatment for that use since warfarin was introduced in the 1950s.Neither Pradaxa nor Xarelto were able to claim both superiority and better safety than warfarin, or reduced risk of death.Almost 15 percent of Americans over the age of 80 are believed to have atrial fibrillation and face a fivefold higher risk of stroke if untreated.
In the meantime, warfarin is holding its own, with 33 million U.S. prescriptions filled for atrial fibrillation and other uses last year, according to IMS Health, a healthcare information and services company. Some 2.2 million prescriptions were filled for Pradaxa.
Doctors have less data and familiarity with Xarelto, which is still being rolled out.FDA Drug Safety Communication: FDA study of Medicare patients finds risks lower for stroke and death but higher for gastrointestinal bleeding with Pradaxa (dabigatran.Weak kidneys allow the medicine to build to unsafe levels in the bloodstream.So the lopsided number of Pradaxa reports compared with warfarin may not indicate an elevated risk, he said.None Available To Help Patients Who Undergo Emergency Surgery Or When There Is Life-Threatening Uncontrolled Bleeding.But when it comes to there being a specific reversal agent to stop an acute bleed once it start, Eliquis and Xarelto (as well as Savaysa) share the dubious distinction of not currently having one that is FDA-approved for use.
Eliquis is eliminated mainly by the liver, which some doctors say could make it more appropriate than Pradaxa or Xarelto for older patients and those with kidney problems.